Migraine • Mar 7, 2024
Migraine is a common disorder which causes a disabling headache usually associated with nausea / vomiting and/ or light and Sound sensitivity. It is the second most common headache disorder overall and is the most common headache presenting to clinicians. It has a prevalence of 17 percent in females and 6 percent in males.
Migraine headache has strong genetic association and is considered to occur secondary to activation of pain sensitive neurons in response to various environmental stimuli along with physiological and Psychological states.
Inadequate sleep, hunger, lights, sounds, symptoms, and several food types are considered.
Pulsatile or throbbing headache that is commonly unilateral (one sided) but can affect both sides or even entire head along with neck sometimes.
Patients can also have pain around the eyes and pain increases with movement and physical activity.
Monosodium Glutamate [अजिना मोटो], Sleep disturbances, alcohol, chocolates, stress, lights, smoke, hunger, stress etc.
Schedule, regular exercise, managing or avoiding triggers
There are wide range of Mediations which can be used to terminate the migraine attacks.
These agents can be given either orally or through other routes.
Conclusion like Intranasal, intramuscular or intravenous depending upon severity along with a combination of Symptoms.
- Acetaminophen (Paracetamol)
- NSAIDS (Naproxen, Ibuprofen, Diclofenac, ketorolac etc.)
-Triptans (Sumatriptan, Rizatriptan, Zolmitriptan etc.)
To prevent recurrence and to reduce Frequency of attack, preventive therapy is used. Patient with frequent attack and even a single extended which is longer (>12 hours)
(3–4 attacks/month)require preventive therapy. Patients need these therapy for at least (6–8) months for proper benefit.
- Amitriptyline / Nortriptyline
- Divalproex sodium
-Propranolol
-Topiramate
Migraine is the most Common Cause of headache related disability worldwide. It has a strong genetic component and has various triggers. Frequency of headache attack can be significantly reduced with proper preventive therapy there by ameliorating a patient’s quality of life.